It definitely will. I'm running one ui 6 on my s22 ultra already, but it's only the beta version and its only had 2 beta updates, the first update was smooth fluid in ma battery was lasting 2 days now with the 2nd beta my battery has took a hit and it doesn't feel as smooth and fluid as it was. Ive a couple of issues now 1 is if I go to open an app on my home screen sometimes the notification panel comes down and 2 battery has took a hit and 3 it just doesn't feel as fast or smooth as the first beta. I says the first beta feels like a stable build for me it felt like it my phone was running brilliant then the 2nd beta has just messed a few things up. Wish they would hurry up and release either beta 3 or the stable release but who knows when it comes to Samsung.