Since last update (27th July one UI 6.1) I've had to remove the SIM that was in slot 2 as it was taking over all calls data etc... I've tried everything swapping the SIMs, replacing SIM2 with eSIM. Phone has been restarted countless times... Husband's phone (S21 Ultra) is the same. 2nd SIM has been removed prom phone and SIM Manager doesn't show it but it works...
I haven't done a factory reset but I'm tempted.