Am having the exact same problem - also on S22U with MS launcher
Cant' replicate on my device. Are you using gestures (i do)?
Same for me, on an old S10e, really annoying. Have you solved this problem?
The problem with mine is upon quick succession from any app (I'm using Niagara Launcher) to home screen, the phone fails the register its first tap. Instead it takes 1-1.5secs to register the tap upon taping next. This only happens while using any other launchers apart from OneUI home. This is very stupid on Samsung's part. They must fix it.