Yes you can do this using a macro app such as Macrodroid or Tasker. I prefer the UI of Macrodroid.
What you can do is set a trigger, an action, and a constraint. For example, the trigger can be a geo fence, for example your home or work, so when you enter the location, the trigger fires the action. The action can be to disconnect from a bluetooth device, such as the one you want. A constraint can be added, such as to only fire on weekdays or at certain times.
So the end result would be, you enter the location boundary/geo fence, then the specific Bluetooth device is disconnected.
The list of triggers, actions and constraints is vast and there is much you can do with these apps.
