No issue on my Samsung Note 10+ 5G after the Android 10 / Samsung One Ui 2.0 update.
If the phone is working fine in safe mode then one or more of your downloaded apps could be causing this. Start deleting the most recent apps until the issue stops.
Then if this was me I would then let the developer of the app know of the bug.
My advice comes from being a UK Samsung Phone Owner.
I have no affiliation with Samsung.
Current Phone ~
Samsung Note 10 Plus 5G _256Gb >_ Samsung One Ui 2.5/ Android 10.